SciencePalSciencePal
SciencePal 2.0

SciencePal 2.0

The Agent Evolves Itself · Multi-Agent Research Platform

SciencePal is a multi-agent research assistant developed by CityU HKAI-SCI. Through natural conversation, delegate literature review, data analysis, code execution, and report writing to domain-specialized agents running in isolated sandboxes — your trusted AI research partner.

Domain Expert Agents

Covering biology, materials, medicine, surveys, MIMIC clinical data, and more — queries are automatically routed to the best-fit agent.

Sandbox as Computer

Each task runs in an isolated Daytona sandbox with Shell, browser, file I/O, and code execution — transparent and auditable.

Self-Evolving Agents

Skills, Memory, Subagents, and knowledge graphs evolve together — agents learn your research habits over time.

SciencePal 2.0 Core Upgrades

Four capability modules — from tool use to self-growth

v2.0.0

Skills · Reusable Know-How

  • Skill-Creator builds more domain skills automatically
  • Built-in bio, medical, and materials skill packs
  • Pluggable — drop in and auto-discover on load
v2.0.1

Memory · Persistent Recall

  • BM25 keyword + HNSW vector hybrid retrieval
  • 5 typed memory classes, injected at session start
  • High-value memories can graduate into Skills
v2.0.2

Subagent · Parallel Work

  • Parent delegates to children — general, explore, plan roles
  • One agent, many workers in parallel
  • Max 10 concurrent, no nesting for controllability
v2.0.3

Knowledge Graph · Your Library

  • Two-pass extraction: AST structure + semantic understanding
  • Confidence and provenance on every edge
  • Wiki articles per community — build your research library

Platform Core Features

End-to-end capabilities for delegating, executing, and collaborating on research tasks

Domain Agents

Pre-built experts across a dozen research fields — the system matches each question to the best agent.

Quick select on workspace · @ mention to switch

Agent Co-Building

Create and configure custom agents with tailored prompts, tools, and collaboration settings.

Drafts · audit trail · team sharing

Isolated Sandbox

Each task runs in a secure, isolated environment with command execution, browsing, and file operations.

Live desktop view · save or revert changes

Personal Knowledge Base

Manage your literature and documents, linked to agent tasks for retrieval and citation.

Upload · semantic search · in-conversation citation

Skills Ecosystem

Reusable skill documents extend agent capabilities for literature, visualization, writing, and more.

On-demand loading · continuous evolution · external platforms

Self-Evolution

Agents learn and improve over time as memory and skills grow together.

Memory retention · skill upgrades · multi-agent coordination

Platform Integration

Ask SciencePal from Feishu, WhatsApp, and other tools — same quality replies as the web app.

Message sync · async delivery · consistent across devices

Observability & Collaboration

Track task progress, share results, and receive email notifications at key milestones.

Share links · execution replay · email alerts

Domain Agents Overview

Select an agent on the workspace or @ mention in chat — the system finds the right domain expert

General Agent

General-purpose agent for all types of scientific questions

Biology Agent

Focused agent for structural biology and bioinformatics analysis

Materials Agent

Specialized agent for materials science

Survey Agent

Professional academic survey agent for systematic literature review and comprehensive survey report generation

AMix Agent

Advanced AMix agent for protein engineering and molecular interaction design

Medical Agent

Structured health consultation and clinical triage guidance; emergency red flags; not for diagnosis

MIMIC Agent

Faithfully reproduce MIMIC-IV workflows from the literature with read-only SQL, statistics, figures, and full transparency

Plasma Agent

Specialized agent for plasma properties research

Antibody Agent

Specialized agent for antibody sequence analysis, developability assessment, antibody-antigen modeling, and candidate antibody design

More domain agents are coming soon — co-building welcome. Custom agents are also supported.

Product Experience Journey

Four steps from question to result

Step 1 · Workspace

Pick an agent and describe your task

After sign-in, open the workspace, choose a domain agent, and describe your need — or start from an example prompt. Send to create a session and enter the execution view.

  • Switch between agents in one click: General, Biology, Materials, Survey, and more
  • Built-in example prompts to get started quickly
  • Configure web search, email notifications, and other preferences
  • One click to send — the system opens the task view automatically
Step 1 · Workspace
GeneralBioMaterialsReview
Step 2 · Task Conversation

Watch progress in real time — ask follow-ups or stop anytime

The conversation view shows the agent's reasoning on the left; the action panel on the right displays tool steps, generated files, and the remote desktop.

  • Click a tool tag in a message to jump to the matching step in the panel
  • Preview files as the agent writes them
  • Follow up, stop the task, switch models, or enable deep thinking
  • Generate a share link so others can view the task and results
Step 2 · Task Conversation
Run command
Action panel
Step 3 · Sandbox

The sandbox is the agent's dedicated computer

Each task runs in an isolated sandbox where the agent executes commands, browses the web, and reads or writes files — all visible in the action panel.

  • Web search and academic literature retrieval built in
  • Complex tasks can dispatch multiple sub-agents in parallel
  • Save or discard sandbox changes before the task ends
  • Watch the agent work in the sandbox in real time
Step 3 · Sandbox
TerminalBrowserFiles
$ pip install pandas
Successfully installed
Save
Discard
Step 4 · Project Management

History, search, and organization

The project sidebar lists all past sessions: start new chats, search past content, rename, share, or delete in bulk.

  • Clear status indicators: running, completed, failed, or stopped
  • Full-text search across projects with highlighted matches
  • Quick access to knowledge base, skills, and platform integrations from the sidebar menu
  • Keyboard shortcut to collapse or expand the sidebar
Step 4 · Project Management
New chat
Search projects…
Protein structure analysis
Literature review draft
MIMIC cohort reproduction

Extend SciencePal into your workflow

Core capabilities available beyond the web browser

Personal Knowledge Base

Access from the sidebar to upload and manage literature, building a personal library for agent retrieval and analysis.

Skills Package

Download the official skills package and follow the setup guide to connect OpenClaw, Claude Code, and other external agent environments.

Platform Integration

Link Feishu or WhatsApp to ask SciencePal from messaging apps with the same replies as on the web.

Session Sharing

Generate share links for read-only viewing of the full conversation and execution — ideal for demos, reports, and teamwork.

Ready to get started with your research?

Describe your question in natural language — SciencePal automatically routes to the right agent for search, analysis, and reporting.

SciencePal 2.0 — The Agent Evolves Itself !